Question

В результате скрещиваний установили ,что частота кроссинговера между генами равна С-B=8%,D-F=6%,A-B=9%?A-F=4%,A-C=1%,C-D=3%?A-D=2%.Попробуйте определить порядок генов в хромосоме.

Answer 1

Расстояние между генами (по проценту кроссинговера):А-В-С.

Answer 2

Расстояние между генами, расположенными в одной хромосоме, определяется по проценту кроссинговера между ними и прямо пропорционально ему. Тогда для расстояний имеем AB меньше BC меньше AC, откуда получаем вероятный порядок A-B-C. По-моему так.

Answer 3

Determining the gene order in a chromosome based on crossover frequencies

The question provides crossover frequency percentages between different gene pairs obtained from genetic crosses. Let's analyze this data step-by-step:

The gene pair A-B has the highest crossover frequency of 9%. This suggests that genes A and B are located close to each other on the chromosome.

Gene pairs A-C and C-D have relatively low crossover frequencies of 1% and 3% respectively. This indicates that genes A and C, and genes C and D are located farther apart on the chromosome compared to gene pairs with higher crossover frequencies.

Crossover frequencies between all other gene pairs lie between these high and low values: A-D (2%), A-F (4%), C-F (6%).

Based on this analysis, the most likely order of the genes on the chromosome is: A, B, D, F, C. In this order, all the gene pairs with higher crossover frequencies are located closer together on the chromosome, while those with lower frequencies are farther apart.

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