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Synthesis of ATP
The synthesis of ATP (adenosine triphosphate) occurs in the mitochondria of eukaryotic cells through a process called oxidative phosphorylation. This process involves the electron transport chain and ATP synthase.
Oxidative Phosphorylation: - The electron transport chain is a series of protein complexes located in the inner mitochondrial membrane. It plays a crucial role in generating a proton gradient across the membrane. - This proton gradient is established through the transfer of electrons from NADH and FADH2 to oxygen, leading to the pumping of protons across the inner mitochondrial membrane.
ATP Synthase: - ATP synthase is an enzyme complex embedded in the inner mitochondrial membrane. It utilizes the energy from the proton gradient to catalyze the synthesis of ATP from ADP (adenosine diphosphate) and inorganic phosphate (Pi) through a process called chemiosmosis.
Overall Process: - The overall process of ATP synthesis in the mitochondria involves the coupling of electron transport and proton pumping to the production of ATP by ATP synthase, resulting in the conversion of ADP and Pi into ATP.
In summary, the synthesis of ATP primarily occurs in the mitochondria of eukaryotic cells through the process of oxidative phosphorylation, involving the electron transport chain and ATP synthase.
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