Question

У пацієнта Б., 35 років, виявлено виразкову хворобу шлунка. Призначте йому комплексне лікування, поясніть дію препаратів. Перелік засобів: альмагель, ацидин-пепсин, омепразол, ранітидин, контрикал, гастроцепін, фестал, алохол, метронідазол. Виберіть необхідні препарати та визначте їх фармакологічні групи.

Answer 1

У пацієнта Б., 35 років, з діагнозом виразкової хвороби шлунка, рекомендовано комплексне лікування, яке включає такі препарати з їхніми фармакологічними групами:

1. Альмагель - антацидний препарат, що зменшує кислотність шлунку та захищає слизову оболонку.

2. Омепразол - інгібітор протонної помпи, що знижує виділення шлункової кислоти та сприяє зціленню виразок.

3. Ранітидин - блокатор H2-рецепторів, що знижує кислотність шлунку та полегшує симптоми виразкової хвороби.

4. Контрикал - протизапальний та протизаразковий препарат, що має антибактеріальну дію проти Helicobacter pylori, головної причини виразкової хвороби.

5. Метронідазол - антибіотик, що використовується для ерадикації Helicobacter pylori.

Врахуйте, що призначення препаратів та їхні дози повинні здійснюватись лише лікарем-гастроентерологом залежно від стану пацієнта та його індивідуальних особливостей.

Answer 2

Complex Treatment for Gastric Ulcer

To treat the gastric ulcer in patient B, a comprehensive approach is required. The following medications have been listed: almagel, acedin-pepsin, omeprazole, ranitidine, contrical, gastrocepin, festal, alohol, and metronidazole. Let's discuss the action of each medication and select the necessary ones for the treatment.

1. Almagel: Almagel is an antacid medication that helps neutralize stomach acid and provides relief from symptoms such as heartburn and indigestion. It contains aluminum hydroxide and magnesium hydroxide as active ingredients. These compounds work by reducing the production of stomach acid and forming a protective coating on the stomach lining [[1]].

2. Acidin-Pepsin: Acidin-Pepsin is a combination medication that contains pepsin, an enzyme that aids in the digestion of proteins, and hydrochloric acid, which helps maintain the acidic environment in the stomach. It is used to improve digestion and relieve symptoms of indigestion [[2]].

3. Omeprazole: Omeprazole belongs to a class of medications called proton pump inhibitors (PPIs). It works by reducing the production of stomach acid, thereby helping to heal and prevent further damage to the stomach lining. Omeprazole is commonly used for the treatment of gastric ulcers and gastroesophageal reflux disease (GERD) [[3]].

4. Ranitidine: Ranitidine is an H2 receptor antagonist that reduces the production of stomach acid. It is used to treat various conditions, including gastric ulcers, GERD, and Zollinger-Ellison syndrome. Ranitidine helps relieve symptoms and promotes healing of the ulcer [[4]].

5. Contrical: Contrical is a proteolytic enzyme preparation that contains trypsin and chymotrypsin. These enzymes help in the breakdown of proteins and have anti-inflammatory properties. Contrical is used to promote tissue repair and reduce inflammation in various conditions, including gastric ulcers [[5]].

6. Gastrocepin: Gastrocepin is an anticholinergic medication that inhibits the action of acetylcholine, a neurotransmitter involved in the stimulation of gastric acid secretion. By reducing gastric acid production, gastrocepin helps in the treatment of gastric ulcers [[6]].

7. Festal: Festal is a combination medication that contains digestive enzymes such as amylase, lipase, and protease. It helps in the digestion of carbohydrates, fats, and proteins. Festal is used to improve digestion and relieve symptoms of indigestion [[7]].

8. Alohol: It seems that "Alohol" might be a misspelling or an incorrect name for a medication. There is no relevant information available regarding a medication with this name.

9. Metronidazole: Metronidazole is an antibiotic that is effective against certain types of bacteria and parasites. It is commonly used to treat infections caused by Helicobacter pylori, a bacterium associated with gastric ulcers. Metronidazole helps eradicate the bacteria and promotes healing of the ulcer [[8]].

Based on the provided list of medications, the following drugs can be selected for the complex treatment of the gastric ulcer:

- Almagel (antacid) - Omeprazole (proton pump inhibitor) - Ranitidine (H2 receptor antagonist) - Contrical (proteolytic enzyme preparation) - Gastrocepin (anticholinergic) - Festal (digestive enzyme preparation) - Metronidazole (antibiotic)

Please note that the selection of medications and their dosages should be determined by a qualified healthcare professional based on the patient's specific condition and medical history. It is important to consult a healthcare provider for personalized advice and treatment.

I hope this information helps! Let me know if you have any further questions.