Question

Ахондроплазии передается как доминантный аутосомный признак. В семье, где оба родителя страдают ахондроплазией, родился нормальный ребенок. Какова вероятность того, что следующий ребенок будет также нормальным?

Answer 1

Надеюсь, что мой почерк понятен. 

Answer 2

Inheritance of Achondroplasia

Achondroplasia is a genetic disorder characterized by short stature and abnormal bone growth. It is caused by a mutation in the FGFR3 gene, which is involved in bone development. Achondroplasia is inherited in an autosomal dominant manner, meaning that a person only needs to inherit one copy of the mutated gene from either parent to develop the condition.

Probability of a Normal Child in a Family with Both Parents Affected by Achondroplasia

In a family where both parents have achondroplasia, there is still a possibility of having a child without the condition. This is because each parent contributes one copy of their genes to their child, and there is a 50% chance that the child will inherit the normal copy of the FGFR3 gene from one of the parents.

Therefore, the probability of the next child being normal in a family where both parents have achondroplasia is 50%.

It's important to note that this probability is based on the assumption that both parents have achondroplasia due to the same mutation in the FGFR3 gene. If the parents have different mutations or if there are other genetic factors at play, the probability may vary.

I hope this information helps! Let me know if you have any other questions.