Question

В результате мутации во фрагменте молекулы белка аминокислота треонин (тре) заменилась на глутамин (глн). Определите аминокислотный состав фрагмента молекулы нормального и мутированного белка и фрагмент мутированной иРНК, если в норме иРНК имеет последовательность: ГУЦАЦАГЦГАУЦААУ. Ответ поясните. Для решения задания используйте таблицу генетического кода

Answer 1

Норм иРНК: ГУЦ-АЦА-ГЦГ-АУЦ-ААУ
норм. полипептид: валин-треонин-аланин-изолейцин-аспаргин
мут. полипептид: валин-глутамин-аланин-изолейцин-аспаргин
мут. иРНК: ГУЦ-ЦАГ-ГЦГ-АУЦ-ААУ

Answer 2

Aminokislota Composition of Normal and Mutated Protein Molecules

When the amino acid threonine (Thr) is replaced by glutamine (Gln) due to a mutation in a protein molecule, it affects the amino acid composition of the molecule. To determine the amino acid composition of the normal and mutated protein molecules, we need to refer to the genetic code table.

The normal RNA sequence provided is: ГУЦАЦАГЦГАУЦААУ.

Using the genetic code table, we can determine the amino acid composition of the normal and mutated protein molecules.

The genetic code table shows the correspondence between codons (sequences of three nucleotides) and the amino acids they encode. By referencing this table, we can determine the amino acid sequence for the given RNA sequence and its mutated form.

Amino Acid Composition of Normal and Mutated Protein Molecules

The normal RNA sequence: ГУЦАЦАГЦГАУЦААУ

The mutated RNA sequence after the threonine (Thr) is replaced by glutamine (Gln): ГУЦАЦАГЦГАУГААУ

Using the genetic code table, we can determine the amino acid composition of the normal and mutated protein molecules.

For the normal RNA sequence: - ГУЦ encodes for the amino acid serine (Ser) - АЦА encodes for the amino acid threonine (Thr) - ГЦГ encodes for the amino acid alanine (Ala) - АУЦ encodes for the amino acid serine (Ser) - ААУ encodes for the amino acid lysine (Lys)

For the mutated RNA sequence: - ГУЦ encodes for the amino acid serine (Ser) - АЦА encodes for the amino acid threonine (Thr) - ГЦГ encodes for the amino acid alanine (Ala) - АУГ encodes for the amino acid methionine (Met) - ААУ encodes for the amino acid lysine (Lys)

Therefore, the amino acid composition of the normal protein molecule is: Ser-Thr-Ala-Ser-Lys And the amino acid composition of the mutated protein molecule is: Ser-Thr-Ala-Met-Lys

This mutation results in the replacement of alanine with methionine in the mutated protein molecule.

This information is based on the genetic code table and the provided RNA sequences.