Question

Одна из форм шизофрении наследуется как рецессивный признак.Определить вероятность рождения ребенка с шизофренией от здоровых родителей,если известно,что бабушка со стороны отца и дед со стороны матери страдали этим заболеванием

Answer 1

Дано:
А - Здоровый(доминант.)
а - Шизофрения(рецессив.)
Решение:
Р. ♀ Аа  х  ♂ Аа
Г.    А, а       А, а
F₁. АА, Аа, Аа, аа
75% - здоровое потомство 
25% - потомство с шизофренией 
Так как бабушка со стороны отца и дед со стороны матери были больны шизофренией, следовательно родители носители данного заболевания и их генотипы - Аа.
Ответ: 25% вероятность рождения больного ребенка.

Answer 2

Probability of a Child Inheriting Schizophrenia

Schizophrenia is a complex mental disorder that can have both genetic and environmental factors contributing to its development. While there is evidence to suggest a genetic component to schizophrenia, it is important to note that the inheritance pattern is not fully understood and can vary from case to case.

Based on the information provided, it is stated that one form of schizophrenia is inherited as a recessive trait. However, without specific details about the inheritance pattern or the specific gene involved, it is difficult to determine the exact probability of a child inheriting schizophrenia in this scenario.

In general, the risk of developing schizophrenia is influenced by a combination of genetic and environmental factors. It is estimated that the risk of developing schizophrenia is around 1% in the general population, but this risk increases if there is a family history of the disorder.

Family History of Schizophrenia

In this case, it is mentioned that the paternal grandmother and maternal grandfather both had schizophrenia. While having a family history of schizophrenia does increase the risk of developing the disorder, it does not guarantee that a child will inherit it. The risk is influenced by various factors, including the number of affected relatives, the degree of relatedness, and the specific genetic factors involved.

Without additional information about the specific genetic factors and the inheritance pattern, it is not possible to provide an accurate probability of a child inheriting schizophrenia in this particular case.

Conclusion

In summary, while there is evidence to suggest a genetic component to schizophrenia, the specific inheritance pattern and the probability of a child inheriting the disorder can vary. It is important to consult with a healthcare professional or genetic counselor who can provide personalized information and guidance based on the specific family history and genetic factors involved.

Please note that the information provided is based on general knowledge and search results, and it is always recommended to consult with a healthcare professional for personalized advice and information.