
У человека локус резус-фактора сцеплен с локусом определяющей формы эритроцитов и нахоиться от него
на расстоянии 3 морианид. Резус-положительно и ллиптоцитоз определяется доминантными оутосомными генами .Один из супругов гетерозиготен по обоим признакам. ПРи этом резус-положительность он унаследовал от первого родителя, ллиптоцитоз от другого. Второй супруг резус-отрицателен и имеет нормальные эритроциты. Определить процентное соотношение вероятного фенотипа и генотипа.

Ответы на вопрос




Understanding the Question
The question is asking for the percentage of the probable phenotype and genotype based on the given information about the linkage of the Rh factor locus with the locus determining the shape of erythrocytes, as well as the dominance of autosomal genes for Rh positivity and elliptocytosis. One of the spouses is heterozygous for both traits, while the other spouse is Rh-negative and has normal erythrocytes.
Answer
To determine the percentage of the probable phenotype and genotype, we need to consider the inheritance patterns of the Rh factor and elliptocytosis, as well as the genotypes of the parents.
1. Inheritance of Rh Factor: - The Rh factor is determined by a gene located on an autosome. - Rh positivity is dominant, while Rh negativity is recessive. - One of the spouses is Rh-positive, which means they have at least one dominant allele for Rh positivity. - The other spouse is Rh-negative, which means they have two recessive alleles for Rh negativity.
2. Inheritance of Elliptocytosis: - Elliptocytosis is also determined by a gene located on an autosome. - Elliptocytosis is caused by a dominant allele, while normal erythrocytes are determined by a recessive allele. - One of the spouses has elliptocytosis, which means they have at least one dominant allele for elliptocytosis. - The other spouse has normal erythrocytes, which means they have two recessive alleles for normal erythrocytes.
Based on this information, we can determine the probable phenotype and genotype of their offspring.
Probable Phenotype
The probable phenotype refers to the observable traits of an individual. In this case, we need to determine the percentage of offspring with Rh-positive and Rh-negative blood types, as well as the percentage with elliptocytosis and normal erythrocytes.
1. Rh Factor: - The Rh factor is determined by a single gene with two alleles: Rh-positive (dominant) and Rh-negative (recessive). - The Rh-positive parent is heterozygous for the Rh factor, meaning they have one dominant allele and one recessive allele. - The Rh-negative parent is homozygous recessive for the Rh factor, meaning they have two recessive alleles. - The possible genotypes for the Rh factor are: Rh-positive (RR or Rr) and Rh-negative (rr). - The possible phenotypes for the Rh factor are: Rh-positive and Rh-negative.
Based on the given information, the probable percentage of Rh-positive offspring is 50%, and the probable percentage of Rh-negative offspring is 50%.
2. Elliptocytosis: - Elliptocytosis is determined by a single gene with two alleles: elliptocytosis (dominant) and normal erythrocytes (recessive). - The parent with elliptocytosis is heterozygous for the elliptocytosis gene, meaning they have one dominant allele and one recessive allele. - The parent with normal erythrocytes is homozygous recessive for the elliptocytosis gene, meaning they have two recessive alleles. - The possible genotypes for elliptocytosis are: elliptocytosis (EE or Ee) and normal erythrocytes (ee). - The possible phenotypes for elliptocytosis are: elliptocytosis and normal erythrocytes.
Based on the given information, the probable percentage of offspring with elliptocytosis is 50%, and the probable percentage of offspring with normal erythrocytes is 50%.
Probable Genotype
The probable genotype refers to the genetic makeup of an individual. In this case, we need to determine the percentage of offspring with different combinations of alleles for the Rh factor and elliptocytosis.
1. Rh Factor: - The Rh-positive parent is heterozygous for the Rh factor, meaning they have one dominant allele (R) and one recessive allele (r). - The Rh-negative parent is homozygous recessive for the Rh factor, meaning they have two recessive alleles (rr). - The possible genotypes for the Rh factor in the offspring are: RR, Rr, and rr.
Based on the given information, the probable percentage of offspring with the genotype RR is 25%, the probable percentage with the genotype Rr is 50%, and the probable percentage with the genotype rr is 25%.
2. Elliptocytosis: - The parent with elliptocytosis is heterozygous for the elliptocytosis gene, meaning they have one dominant allele (E) and one recessive allele (e). - The parent with normal erythrocytes is homozygous recessive for the elliptocytosis gene, meaning they have two recessive alleles (ee). - The possible genotypes for elliptocytosis in the offspring are: EE, Ee, and ee.
Based on the given information, the probable percentage of offspring with the genotype EE is 25%, the probable percentage with the genotype Ee is 50%, and the probable percentage with the genotype ee is 25%.
Summary
Based on the given information, the probable percentage of the offspring's phenotype and genotype can be summarized as follows:
1. Probable Phenotype: - Rh-positive: 50% - Rh-negative: 50% - Elliptocytosis: 50% - Normal erythrocytes: 50%
2. Probable Genotype: - RR: 25% - Rr: 50% - rr: 25% - EE: 25% - Ee: 50% - ee: 25%
Please note that these percentages are based on the given information and assume independent assortment of the genes involved. The actual percentages may vary in practice due to factors such as genetic recombination and other genetic factors that were not specified in the question.
I hope this helps! Let me know if you have any further questions.


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