Question

В семье у здоровых родителей родился ребёнок ,страдающий глухотой .Супруги обратились в медиков генетическую консультацию с целью проанализировать вероятность рождения слндущего ребёнка тоже глухим .Родители обоих супругов имели хороший слух у бабушки со стороны жены глухими были её брат и мать (пробабушка).По линии мужа глухота была у родной сёстры дедушки .Как наследуется данный признак ?Какое заключение дал генетик ?

Answer 1

Что это все передается по наследству если даже родители здоровые это все таки гены

Answer 2

Inheritance of Deafness and Genetic Consultation

When a child is born with deafness in a family with healthy parents, it is natural for the parents to seek genetic consultation to understand the likelihood of having another deaf child. In this case, both sets of parents have good hearing, but there is a history of deafness in the family. The wife's side of the family includes a deaf brother and mother, while on the husband's side, there is a deaf sister of the grandfather.

Inheritance Pattern of Deafness

Deafness can be caused by various factors, including genetic mutations. The inheritance pattern of deafness depends on the specific genetic cause. There are two main types of inheritance patterns for deafness: autosomal dominant and autosomal recessive.

1. Autosomal Dominant Inheritance: If deafness is inherited in an autosomal dominant manner, it means that a single copy of the mutated gene is sufficient to cause deafness. In this case, if one parent carries the mutated gene, there is a 50% chance of passing it on to each child. However, it is important to note that not all cases of deafness are inherited in an autosomal dominant manner.

2. Autosomal Recessive Inheritance: If deafness is inherited in an autosomal recessive manner, it means that both copies of the gene must be mutated for deafness to occur. In this case, if both parents are carriers of the mutated gene (meaning they have one normal copy and one mutated copy), there is a 25% chance of having a deaf child with each pregnancy. There is also a 50% chance of having a child who is a carrier of the mutated gene but does not have deafness.

It is important to note that these are general inheritance patterns, and the specific genetic cause of deafness can vary. Genetic testing and counseling can provide more accurate information about the inheritance pattern in a specific case.

Conclusion of the Genetic Consultation

The genetic counselor would consider the family history, the mode of inheritance, and any available genetic testing results to provide a conclusion. Without specific information about the genetic cause of deafness in this case, it is not possible to provide a definitive conclusion. However, the genetic counselor would likely discuss the possibility of both autosomal dominant and autosomal recessive inheritance patterns based on the family history provided.

The counselor may recommend further genetic testing to identify the specific genetic cause of deafness in the family. This information would help provide more accurate predictions about the likelihood of having another deaf child in the future.

It is important to remember that genetic consultations are personalized and take into account the specific circumstances of each family. Therefore, it is recommended for the parents to consult with a genetic counselor or healthcare professional to receive accurate and personalized information regarding their situation.